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spo0M
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spo0M

sporulation-control gene
locus
BSU_08760
pI
4.28
mw
29.56 kDa
protein length
258 aa Sequence Blast
gene length
777 bp Sequence Blast
function
sporulation
product
unknown
essential
no
synonyms
ygaI
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.3|Sporulation/ other]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.2|Cell envelope stress proteins (controlled by SigM, V, W, X, Y)]

    • Gene

    Coordinates
    953,373 954,149

    Phenotypes of a mutant

  • Blocked at stage zero of [SW|sporulation] and is susceptible to lysis during vegetative growth [Pubmed|9795118]

    • The protein

    Protein family

  • spo0M family (single member, according to UniProt)

    • Effectors of protein activity

  • the protein is degraded by the [protein|4E7B9426CED372AA8A321A147116A3A589FBF20C|FtsH] metalloprotease [Pubmed|22142536]

    • Structure

  • [PDB|5CL2] [Pubmed|26625291]

    • [SW|Localization]

  • scattered distribution pattern in cells, appearing near the cell poles and the septum region [pubmed|28234965]

    • Expression and Regulation

    Operons

    genes
    [gene|86BEE9B4DEA83B3B8EFC52EFDDC1F62314FC4291|spo0M]
    description
    [Pubmed|9795118]

    sigma factors

  • [protein|DC3449D5F195E5C2E9E14FEC95396C8F1FDF73B4|SigH]: sigma factor, [Pubmed|9795118], in [regulon|DC3449D5F195E5C2E9E14FEC95396C8F1FDF73B4|SigH regulon]
  • [protein|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|SigW]: sigma factor, [Pubmed|11866510], in [regulon|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|SigW regulon]

    • additional information

  • the protein is degraded by the [protein|search|FtsH] metalloprotease [PubMed|22142536]
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    Biological materials

    Mutant

  • BKE08760 ([gene|86BEE9B4DEA83B3B8EFC52EFDDC1F62314FC4291|spo0M]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE08760 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTAGATCTTCCCCTTT, downstream forward: _UP4_TAAGTATAAAAAGGAGCCGA
  • BKK08760 ([gene|86BEE9B4DEA83B3B8EFC52EFDDC1F62314FC4291|spo0M]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK08760 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTAGATCTTCCCCTTT, downstream forward: _UP4_TAAGTATAAAAAGGAGCCGA

    • References

    Reviews

  • 28577219

    • Original publications

  • 9795118,11866510,22142536,26625291,28234965