rsbS [2017-07-24 10:07:54]

locus: BSU04680

pI: 4.14

mw: 13.17 kDa

protein length: 121 aa

gene length: 363 bp

function: control of [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB] activity

product: scaffold protein of the stressosome, anti-[protein|ADC52A22950736A0435AEEEC43F7407878786A81|RsbT]

essential: no

synonyms: ycxS

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.2|Control of sigma factors]
• [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.5|Phosphorylation on a Ser residue]

Gene

Coordinates: 520,237 → 520,602

The protein

Modification

• phosphorylation on Ser-59 by [protein|ADC52A22950736A0435AEEEC43F7407878786A81|RsbT] [Pubmed|17218307], dephosphorylation by [protein|8536803BDFB58D43C52961931F609933E49E989D|RsbX] [Pubmed|21362065]

Structure

• [PDB|3VY9] (complete stressosome)

Expression and Regulation

Operons

• genes: [gene|621357D1FB6AC1B0499732EFE226F982B26CE34E|rsbR]-[gene|841CE7FCA4E84445830CA18F9856F6F30014E3BB|rsbS]-[gene|ADC52A22950736A0435AEEEC43F7407878786A81|rsbT]-[gene|0B8381D2C724DAA724E4AFC67000F12AD112D13D|rsbU]-[gene|AC64DA463250A090A62E50901EFE653C8F963872|rsbV]-[gene|5AF5F199C5D92E13DE1C56E28948A557E3954CBF|rsbW]-[gene|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]-[gene|8536803BDFB58D43C52961931F609933E49E989D|rsbX]
  description: [Pubmed|8002610]

  sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|8002610], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]
  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [Pubmed|11544224], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]

  regulatory mechanism

  • [protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA]: repression, [Pubmed|20454630], in [regulon|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA regulon]

  regulation

  • ''[protein|search|rsbV]:'' induced by stress ([protein|search|SigB]) [Pubmed|11544224]

Labs working on this gene/protein

• [SW|Bill Haldenwang], San Antonio, USA
• [SW|Chet Price], Davis, USA [http://foodscience.ucdavis.edu/price_lab/pricelab.html homepage]
• [SW|Rick Lewis], Newcastle, UK [http://www.ncl.ac.uk/camb/staff/profile/r.lewis homepage]

References

Reviews

• 19704888,16319496,20658979,28271471

Original Articles

• 8002610,8682769,9786195,8682789,10781545,15583165,8824586,10329124,17158665,21821766,16321960,10671474,8808936,15312768,11244072,15342582,16321960,8955331,12950928,15466036,9179850,18832644,17218307,20019076,24599254,23320651,21362065,28727759