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ctaB [Wed Jan 20 2016 14:32:53 GMT+0100 (CET)]
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ctaB [Wed Jan 20 2016 14:32:53 GMT+0100 (CET)]

heme O synthase (major enzyme)
locus
BSU14880
pI
9.00
mw
33.00 kDa
function
heme biosynthesis
product
heme O synthase (major enzyme)
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.6|Biosynthesis of heme/ siroheme]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • [SW|Categories] containing this gene/protein

  • [SW|biosynthesis of cofactors], [SW|membrane proteins]

    • This gene is a member of the following [SW|regulons]

  • [SW|ResD regulon]

    • Gene

    Coordinates on the chromosome (coding sequence)
    1,559,309 -> 1,560,226

    Phenotypes of a mutant

  • inactivation of ''ctaB'' facilitates without a wall (due to reduction of oxidative stress) [Pubmed|26051891]

    • The protein

    Protein family

  • ubiA prenyltransferase family, Protoheme IX farnesyltransferase subfamily (according to Swiss-Prot)

    • Paralogous protein(s)

  • [protein|search|CtaO]

    • [SW|Localization]

  • cell membrane (according to Swiss-Prot)

    • Expression and Regulation

    Operon

  • ''[protein|search|ctaB]-[protein|search|ctaC]-[protein|search|ctaD]-[protein|search|ctaE]-[protein|search|ctaF]-[protein|search|ctaG]'' [Pubmed|9829923]

    • Regulation

  • expressed under anaerobic conditions ([protein|search|ResD]) [Pubmed|9829923]

    • Regulatory mechanism

  • [protein|search|ResD]: transcription activation [Pubmed|9829923]

    • References

  • 7968515,15491161,9829923,19204012,26051891