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dra [Mon Aug 31 2015 13:57:38 GMT+0200 (CEST)]
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dra [Mon Aug 31 2015 13:57:38 GMT+0200 (CEST)]

deoxyribose-phosphate aldolase
locus
BSU39420
pI
4.93
mw
22.00 kDa
function
utilization of nucleotides as carbon source
product
deoxyribose-phosphate aldolase
essential
no
ec
4.1.2.4
synonyms
deoC
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.5|Nucleotide metabolism] → [category|SW 2.5.1|Utilization of nucleotides]
    • syns
    deoC

    [SW|Categories] containing this gene/protein

  • [SW|utilization of nucleotides]

    • This gene is a member of the following [SW|regulons]

  • [SW|CcpA regulon], [SW|DeoR regulon]

    • The protein

    Catalyzed reaction/ biological activity

  • 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde (according to Swiss-Prot)

    • Protein family

  • DeoC type 1 subfamily (according to Swiss-Prot)

    • Structure

  • [PDB|1MZH] (from ''Aquifex aeolicus'', 42% identity, 62% similarity)

    • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)

    • Expression and Regulation

    Operon

  • ''[protein|search|dra]-[protein|search|nupC]-[protein|search|pdp]'' [Pubmed|8550462]

    • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|8550462]

    • Regulation

  • repressed by glucose ([protein|search|CcpA]) [Pubmed|10666464]
  • induced by deoxynucleotides ([protein|search|DeoR]) [Pubmed|8550462]

    • Regulatory mechanism

  • [protein|search|CcpA]: transcription repression [Pubmed|10666464]
  • [protein|search|DeoR]: transcription repression [Pubmed|8550462]

    • References

  • 10666464,11065368,8550462,10074062