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sspA [Mon Sep 21 2015 16:47:31 GMT+0200 (CEST)]
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sspA [Mon Sep 21 2015 16:47:31 GMT+0200 (CEST)]

small acid-soluble spore protein (major alpha-type SASP)
locus
BSU29570
pI
4.00
mw
6.00 kDa
function
protection of spore DNA
product
small acid-soluble spore protein (major alpha-type SASP)
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.3|Small acid-soluble spore proteins]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.1|Phosphorylation on an Arg residue]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.5|Phosphorylation on a Ser residue]

    • [SW|Categories] containing this gene/protein

  • [SW|sporulation proteins], [SW|phosphoproteins]

    • This gene is a member of the following [SW|regulons]

  • [SW|SigG regulon], [SW|SpoVT regulon]

    • Gene

    Phenotypes of a mutant

  • a ''[protein|search|sspA]'' mutant is sensitive to ionizing radiation [Pubmed|24123749]

    • The protein

    Protein family

  • alpha/beta-type SASP family (according to Swiss-Prot)

    • Modification

  • phosphorylated on Ser-6, Ser-9-, Ser-47, and Ser-55 [Pubmed|26381121]

    • Structure

  • [PDB|2BZ0] (82% identity, 89% similarity)

    • Expression and Regulation

    Operon

  • ''[protein|search|sspA]'' [Pubmed|3009398]

    • [SW|Sigma factor]

  • [protein|search|SigG] [Pubmed|15699190]

    • Regulation

  • expressed late during sporulation in the forespore ([protein|search|SigG], [SW|SpoVT]) [Pubmed|15699190,8755877]

    • Regulatory mechanism

  • [SW|SpoVT]: transcription activation [Pubmed|8755877]

    • Biological materials

    Mutant

  • BP137 (''[protein|search|sspA]''::''cat'') available in [SW|Fabian Commichau]'s lab
  • 1S109 (no resistance), available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S109&Search=1S109 BGSC]
  • 1S111 (no resistance), [Pubmed|3087950], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S111&Search=1S111 BGSC]
  • 1S112 (no resistance), [Pubmed|3125155], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S112&Search=1S112 BGSC]
  • 1S113 (no resistance), [Pubmed|3125155], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S113&Search=1S113 BGSC]

    • References

  • 16707666,2456528,3009398,12884008,11092849,7608092,15458366,19542328,15699190,8755877,23064347,3087950,3125155,24123749,26381121