iron/citrate ABC transporter (permease)
product
iron/citrate ABC transporter (permease)
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.5|Uptake of iron/ siderophores][category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.3|Acquisition of iron] → [category|SW 1.3.3.1|ABC transporters for the uptake of iron/ siderophores][category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.5|Iron metabolism] → [category|SW 2.6.5.4|ABC transporters for the uptake of iron/ siderophores][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|ABC transporters], [SW|acquisition of iron], [SW|iron metabolism], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|Fur regulon]Gene
Coordinates on the chromosome (coding sequence)
823,716 -> 824,717
The protein
Protein family
FecCD subfamily (according to Swiss-Prot)Structure
[PDB|4G1U] (from ''Yersinia pestis'', the [SW|YfmD]-[SW|YfmE]-[SW|YfmF] complex, 37% identity) [Pubmed|23142986][PDB|4R9U], the ''E. coli'' BtuC-BtuD complex, BtuC shares 35% identity, 66% similarity with YfmE, [Pubmed|25402482][SW|Localization]
cell membrane [Pubmed|10092453][SW|Interactions]
[protein|search|YfmF]-([protein|search|YfmD]-[protein|search|YfmE])-([protein|search|YfmC]-[protein|search|YhfQ]) [Pubmed|10092453]Expression and Regulation
Operon
''[protein|search|yfmC]-[protein|search|yfmD]-[protein|search|yfmE]-[protein|search|yfmF]'' [Pubmed|16672620]Regulation
induced upon iron starvation ([protein|search|Fur]) [Pubmed|16672620,12354229]Regulatory mechanism
[protein|search|Fur]: transcription repression [Pubmed|16672620,12354229]References
10092453,16672620,25402482,23142986 
