yutK

similar to Na⁺/nucleoside cotransporter

locus: BSU_32180

pI: 9.48

mw: 42.12 kDa

protein length: 404 aa

gene length: 1215 bp

function: unknown

product: unknown

essential: no

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.5|Nucleotide metabolism] → [category|SW 2.5.2|Biosynthesis/ acquisition of nucleotides] → [category|SW 2.5.2.6|Biosynthesis/ acquisition of nucleotides/ other/ based on similarity]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

Gene

Coordinates: 3,307,017 3,308,231

The protein

Protein family

• concentrative nucleoside transporter (CNT) (TC 2.A.41) family (with [protein|4F718681A7AD0C86B2551248570F493AC0B2E7E9|NupC] and [protein|C333F405F597FF260FFA0EC616B8CF6BF454815B|NupG], according to UniProt)

Structure

• [PDB|3TIJ] (from Vibrio cholerae, 54% identity) [pubmed|22407322]

[SW|Localization]

• cell membrane (according to UniProt)

Expression and Regulation

Operons

• genes: [gene|7D4CF2FF4108D3AE170C1EE3C7D494EAD46699C6|yutK]
  description: [Pubmed|22383849]

Biological materials

Mutant

• MGNA-A970 (yutK::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/970 NBRP B. subtilis, Japan]
• BKE32180 ([gene|7D4CF2FF4108D3AE170C1EE3C7D494EAD46699C6|yutK]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE32180 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGAATACTCGTACACCTC, downstream forward: _UP4_TAAACGATAAAAGCTCCTTG
• BKK32180 ([gene|7D4CF2FF4108D3AE170C1EE3C7D494EAD46699C6|yutK]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK32180 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGAATACTCGTACACCTC, downstream forward: _UP4_TAAACGATAAAAGCTCCTTG

References

• 20525796,22407322