pncB [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

putative nicotinate phosphoribosyltransferase

locus: BSU31750

pI: 5.00

mw: 56.00 kDa

function: unknown

product: putative nicotinate phosphoribosyltransferase

essential: yes

ec: 2.4.2.11

synonyms: yueK

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.11|Biosynthesis of NAD(P)]
• [category|SW 2|Metabolism] → [category|SW 2.7|Detoxification reactions]
• [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

[SW|Categories] containing this gene/protein

• [SW|essential genes], [SW|poorly characterized/ putative enzymes]

Gene

Coordinates on the chromosome (coding sequence): 3,259,403 -> 3,260,875

Phenotypes of a mutant

• essential [Pubmed|12682299]

The protein

Catalyzed reaction/ biological activity

• Nicotinate D-ribonucleotide diphosphate = nicotinate 5-phospho-alpha-D-ribose 1-diphosphate (according to Swiss-Prot)

Protein family

• NAPRTase family (according to Swiss-Prot)

Structure

• [PDB|2F7F] (from ''Enterococcus faecalis'', 61% identity)

Expression and Regulation

Operon

• ''[protein|search|pncB]'' [Pubmed|9274030]

References

• 16199587,9274030