SubtiBank SubtiBank
rplGA
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rplGA

similar to ribosomal protein, L7AE family, binds K-turns in RNA switches
locus
BSU_16620
pI
10.17
mw
10.92 kDa
protein length
100 aa Sequence Blast
gene length
303 bp Sequence Blast
function
unknown
product
unknown
essential
no
synonyms
ylxQ,ymxC,rpmXA,ktuQ
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.5|Ribosomal protein/ based on similarity]

    • Gene

    Coordinates
    1,733,687 1,733,989

    The protein

    Catalyzed reaction/ biological activity

  • binds K-turns in [SW|RNA switch]es as the occur in the [protein|search|L-box], the [protein|search|S-box] and the [protein|search|T-box] [Pubmed|22355167]

    • Protein family

  • Eukaryotic ribosomal protein eL8 family (with [protein|11D7ABA61FC4069B48614875AF2C6C694291B545|RplGB], according to UniProt)

    • Structure

  • [PDB|3V7Q] [Pubmed|22355167]

    • [SW|Localization]

  • [SW|ribosome] (according to UniProt)

    • Expression and Regulation

    Operons

    genes
    [gene|9F6C447900410BF64409E5C41A11C76968DADAFA|ylxS]-[gene|8887ADC77C43F21CD375BDAA4D38E940786DAD4F|nusA]-[gene|F4097349A563503468A2A14F062AEAC532C7917A|ylxR]-[gene|7BFA65857F69855DBB3BB64D93B4ED2F09DC705B|rplGA]-[gene|378B77412D0DEA220A97DEC246410509D9B74D46|infB]-[gene|24835CE6CD2E1F183DB9121F29A63101718B5DF9|ylxP]-[gene|B3119A40393A288EF34FC3E9839B6E40AC6A6EA0|rbfA]
    description
    [Pubmed|8491709]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|8491709], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]
  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [Pubmed|15805528,26577401], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]

    • regulatory mechanism

  • [regulon|stringent response|stringent response]: negative regulation, in [regulon|stringent response|stringent response]
  • [protein|8887ADC77C43F21CD375BDAA4D38E940786DAD4F|NusA]: attenuation, [protein|8887ADC77C43F21CD375BDAA4D38E940786DAD4F|NusA] stimulates termination [Reference|http://www.nature.com/articles/nmicrobiol20157], in [regulon|8887ADC77C43F21CD375BDAA4D38E940786DAD4F|NusA regulon]

    • regulation

  • autoregulation [SW|NusA] [http://www.nature.com/articles/nmicrobiol20157 reference]
  • induced by glucose [pubmed|30355672]
    • view in new tab

    Biological materials

    Mutant

  • BKE16620 ([gene|7BFA65857F69855DBB3BB64D93B4ED2F09DC705B|rplGA]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE16620 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GGGAAACCATTCCATTCCAG, downstream forward: _UP4_AATAAGCTGATCAGCTTGCTCG
  • BKK16620 ([gene|7BFA65857F69855DBB3BB64D93B4ED2F09DC705B|rplGA]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK16620 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GGGAAACCATTCCATTCCAG, downstream forward: _UP4_AATAAGCTGATCAGCTTGCTCG

    • References

  • 11948165,8491709,22355167,29280348,26522935