SubtiBank SubtiBank
mnaA
An ordered knock out library of all non-essential genes in B. subtilis is now available at Addgene. Information on ordering a copy can be found here. See Koo et al. 2017 for details about library construction.

mnaA

UDP-N-acetylglucosamine 2-epimerase
locus
BSU35660
pI
5.47
mw
42.48 kDa
protein length
380 aa Sequence Blast
gene length
1140 bp Sequence Blast
function
biosynthesis of teichoic acid
product
UDP-N-acetylglucosamine 2-epimerase
essential
yes
ec
5.1.3.14
synonyms
yvyH

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.4|Biosynthesis of teichoic acid]
  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.1|Biosynthesis of cell wall components] → [category|SW 2.6.1.3|Biosynthesis of teichoic acid]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • Gene

    Coordinates
    3,664,241 → 3,665,383

    Phenotypes of a mutant

  • essential [Pubmed|12682299]
  • The protein

    Catalyzed reaction/ biological activity

  • UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-mannosamine (according to Swiss-Prot)
  • Protein family

  • UDP-N-acetylglucosamine 2-epimerase family (according to Swiss-Prot)
  • Structure

  • [PDB|1O6C] [Pubmed|16021622]
  • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)
  • Biological materials

    Mutant

  • MGNA-B651 (yvyH::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1650 NBRP B. subtilis, Japan]
  • References

    Reviews

  • 24024634
  • Original publications

  • 12107153,16021622,24470206