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nrgA [Wed Sep 23 2015 12:55:19 GMT+0200 (CEST)]
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nrgA [Wed Sep 23 2015 12:55:19 GMT+0200 (CEST)]

ammonium transporter, required at low ammonium concentration
locus
BSU36510
pI
5.00
mw
42.00 kDa
function
ammonium uptake
product
ammonium transporter
essential
no
synonyms
amtB
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.8|Uptake of other small ions]
  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.1|Biosynthesis/ acquisition of glutamate/ glutamine/ ammonium assimilation]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • [SW|Categories] containing this gene/protein

  • [SW|transporters/ other], [SW|biosynthesis/ acquisition of amino acids], [SW|glutamate metabolism], [SW|membrane proteins]

    • This gene is a member of the following [SW|regulons]

  • [SW|TnrA regulon]

    • The protein

    Structure

  • [http://www.ebi.ac.uk/pdbe-srv/view/entry/2nuu/summary 2NUU] (the complex with [protein|search|NrgB], from ''E. coli'') [Pubmed|17220269]

    • [SW|Localization]

  • cell membrane (according to Swiss-Prot), membrane

    • [SW|Interactions]

  • [protein|search|NrgA]-[protein|search|NrgB] [Pubmed|14600241]

    • Expression and Regulation

    Operon

  • ''[protein|search|nrgA]-[protein|search|nrgB]'' [Pubmed|8282685]

    • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|8282685]

    • Regulation

  • induced by ammonium limitation
  • induced by ammonium limitation ([protein|search|TnrA]) [Pubmed|8799114]

    • Regulatory mechanism

  • [protein|search|TnrA]: transcription activation [Pubmed|8799114]

    • Biological materials

    Mutant

  • GP739 (cat), GP255 (''[protein|search|nrgA]-[protein|search|nrgB]'', cat), both available in [SW|Jörg Stülke]'s lab [Pubmed|14600241]
  • 1A920 ( ''nrgA''::''erm''), [Pubmed|8282685], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A920&Search=1A920 BGSC]

    • lacZ fusion

  • pGP168 (in [protein|search|pAC7]), available in [SW|Jörg Stülke]'s lab [Pubmed|14600241]

    • Labs working on this gene/protein

  • [SW|Susan Fisher], Boston, USA [http://www.bumc.bu.edu/microbiology/research/susan-h-fisher-phd/ homepage]

    • References

    Reviews

  • 10637624,17368911

    • Original Publications

  • 12823818,17001076,8799114,14600241,8282685,1670935,17220269,25229891,25755103