mdtR [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

transcription repressor of the multidrug-resistance mdtR-mdtP operon

locus: BSU32870

pI: 6.38

mw: 17.00 kDa

function: regulation of the multidrug-resistance mdtR-mdtP operon

product: transcription repressor (MarR family)

essential: no

synonyms: yusO

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.13|Resistance against toxins/ antibiotics]

[SW|Categories] containing this gene/protein

• [SW|transcription factors and their control], [SW|resistance against toxins/ antibiotics]

This gene is a member of the following [SW|regulons]

• [SW|MdtR regulon]

Gene

Coordinates on the chromosome (coding sequence): 3,374,492 -> 3,374,959

The protein

Structure

• [PDB|1S3J]

Expression and Regulation

Operon

• ''[protein|search|mdtR]-[protein|search|mdtP]'' [Pubmed|19286808]

Regulatory mechanism

• repression by MdtR [Pubmed|19286808]

Biological materials

Mutant

• GP1115 (spc), available in [SW|Stülke] lab

References

• 19286808