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rpsD [Wed Aug 31 2016 18:01:03 GMT+0200 (CEST)]
product
ribosomal protein S4 (BS4)
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.4|Ribosomal proteins][category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes][category|SW 6|Groups of genes] → [category|SW 6.5|Universally conserved proteins][SW|Categories] containing this gene/protein
[SW|translation], [SW|essential genes], [SW|universally conserved proteins]This gene is a member of the following [SW|regulons]
[SW|stringent response]Gene
Coordinates on the chromosome (coding sequence)
3,035,730 -> 3,036,332
Phenotypes of a mutant
essential [Pubmed|23002217,12682299]The protein
Protein family
[SW|ribosomal protein] S4P family (according to Swiss-Prot)Structure
[PDB|1C06] (Geobacillus stearothermophilus)[PDB|3J9W] (the [SW|ribosome]) [Pubmed|25903689]Expression and Regulation
Operon
''[protein|search|rpsD]'' [Pubmed|1699930][SW|Sigma factor]
[protein|search|SigA] [Pubmed|1699930]Regulation
[protein|search|RelA] dependent downregulation (Class I) during stringent response [Pubmed|11948165]autorepression of ''rpsD'' expression upon binding of excess [protein|search|RpsD] to a [SW|RNA switch] in the untranslated region of the ''rpsD'' mRNA [Pubmed|23611891,1906866]expression is reduced during ethanol stress due to the action of the antisense RNA [protein|search|S1136-1134] [Pubmed|26115952]References
1699930,2121712,6420647,1400226,1906866,19653700,11489846,23611891,23002217,25548247,25548248,26115952,25903689