glucose-inhibited division protein, tRNA uridine 5-carboxymethylaminomethyl modification enzyme
function
tRNA modification
product
tRNA uridine 5-carboxymethylaminomethyl modification enzyme
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.8|tRNA modification and maturation][SW|Categories] containing this gene/protein
[SW|translation], [SW|sporulation/ other]This gene is a member of the following [SW|regulons]
[SW|ComK regulon], [SW|DnaA regulon]Gene
Coordinates on the chromosome (coding sequence)
4,209,603 -> 4,211,489
Phenotypes of a mutant
inactivation of ''[SW|gidA]'' reduces sporulation efficiency to 23.9% that of wild type cells; longer mother cells, with some aberrant septa and forespores [Pubmed|26735940]The protein
Protein family
mnmG family (according to Swiss-Prot)Structure
[PDB|3G05] (the protein of ''E. coli'', 51% identity)[SW|Localization]
cytoplasm (according to Swiss-Prot)[SW|Interactions]
[protein|search|GidA]-[protein|search|ThdF] (suggested by interaction of ''E. coli'' counterparts [Pubmed|19801413] and by co-localization on the chromosome)Expression and Regulation
Operon
''[protein|search|thdF]-[protein|search|gidA]-[protein|search|rsmG]-[protein|search|noc]'' [Pubmed|11807071]Regulatory mechanism
[protein|search|ComK]: transcription activation [Pubmed|11948146][protein|search|DnaA]: transcription repression [Pubmed|26020636]References
19801413,11807071,11948146,26020636,26735940 
