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21st International Conference on Bacilli and Gram-Positive Bacteria. Prague, Czech Republic, June 7-11, 2021.
yflS [2017-04-28 10:36:01]
categories[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 22.214.171.124|Transporter for organic acids][category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 126.96.36.199|Utilization of organic acids][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
This gene is a member of the following [SW|regulons][SW|MalR regulon]
829,382 → 830,818
additional informationthe mRNA is stabilized by basepairing with the RoxS RNA [pubmed|28436820]non-protected mRNA is subject to degradation by by [SW|rnjA|RNase J1] [pubmed|28436820]
Catalyzed reaction/ biological activityuptake of malate
Protein familyView classification (according to Swiss-Prot)
[SW|Localization]cell membrane (according to Swiss-Prot)
Expression and Regulation
regulatory mechanism[protein|689CF50691E77E5A40437EF1E6B5083AF7CFCE08|MalR]: activation, in [regulon|689CF50691E77E5A40437EF1E6B5083AF7CFCE08|MalR regulon]
regulationinduced by malate ([protein|689CF50691E77E5A40437EF1E6B5083AF7CFCE08|MalR])
additional informationthe mRNA is substantially stabilized upon depletion of [SW|Rny|RNase Y ][PubMed|21815947]the mRNA is stabilized by basepairing with the [protein|search|RoxS ]RNA [pubmed|28436820]non-protected mRNA is subject to degradation by by [SW|rnjA|RNase J1] [pubmed|28436820]view in new tab
MutantMGNA-C249 (yflS::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2247 NBRP B. subtilis, Japan]GP1450 (cat), available in [SW|Jörg Stülke]'s lab