SubtiBank SubtiBank
mneS [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]
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mneS [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]

secondary manganese (II) efflux pump
locus
BSU06320
pI
5.00
mw
31.00 kDa
function
Mn(II) export
product
manganese (II) efflux pump
essential
no
synonyms
ydxT,yeaB

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.11|Other exporters]
  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.13|Metal ion exporters]
  • [category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.2|Trace metal homeostasis (Cu, Zn, Ni, Mn, Mo)] → [category|SW 1.3.2.2|Manganese]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|transporters/ other], [SW|trace metal homeostasis (Cu, Zn, Ni, Mn, Mo)], [SW|membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|MntR regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    686,962 -> 687,834

    The protein

    Catalyzed reaction/ biological activity

  • efflux of Mn(II) [Pubmed|27748968]
  • Protein family

  • cation diffusion facilitator (CDF) family [Pubmed|27748968]
  • [SW|Localization]

  • cell membrane (according to Swiss-Prot)
  • Expression and Regulation

    Operon

  • ''[SW|mneP]'' [Pubmed|22383849]
  • [SW|Sigma factor]

  • [SW|SigA] [Pubmed|27748968]
  • Regulation

  • expressed at elevated Mn(II) concentrations ([SW|MntR]) [Pubmed|27748968]
  • Regulatory mechanism

  • [SW|MntR]: transcription activation [Pubmed|27748968]
  • References

  • 27748968