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gntK [Fri Sep 18 2015 17:39:20 GMT+0200 (CEST)]
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gntK [Fri Sep 18 2015 17:39:20 GMT+0200 (CEST)]

gluconokinase
locus
BSU40060
pI
5.00
mw
56.00 kDa
function
gluconate utilization
product
gluconokinase
essential
no
ec
2.7.1.12
synonyms

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.13|Utilization of gluconate]
  • [SW|Categories] containing this gene/protein

  • [SW|utilization of specific carbon sources]
  • This gene is a member of the following [SW|regulons]

  • [SW|AbrB regulon], [SW|CcpA regulon], [SW|GntR regulon]
  • The protein

    Catalyzed reaction/ biological activity

  • ATP D-gluconate = ADP 6-phospho-D-gluconate (according to Swiss-Prot)
  • Protein family

  • FGGY kinase family (according to Swiss-Prot)
  • Expression and Regulation

    Operon

  • ''[protein|search|gntR]-[protein|search|gntK]-[protein|search|gntP]-[protein|search|gntZ]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/10746760 PubMed1][http://www.ncbi.nlm.nih.gov/sites/entrez/3020045 PubMed2]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|3020045]
  • Regulation

  • induced by gluconate ([protein|search|GntR]) [Pubmed|3020045]
  • repressed by glucose ([protein|search|CcpA]) [Pubmed|8370661]
  • Regulatory mechanism

  • [protein|search|GntR]: transcription repression [Pubmed|3020045]
  • [protein|search|CcpA]: transcription repression [Pubmed|10666464]
  • [protein|search|AbrB]: transcription activation [Pubmed|20817675]
  • References

  • 3011959,8288545,3037520,2537826,6322857,3020045,10746760,8370661,3020045,1659648,220817675