SubtiBank SubtiBank
ydaK [Sat Dec 17 2016 16:50:55 GMT+0100 (CET)]
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

ydaK [Sat Dec 17 2016 16:50:55 GMT+0100 (CET)]

general stress protein, may act as c-di-GMP receptor
locus
BSU04280
pI
6.00
mw
32.00 kDa
function
unknown
product
general stress protein
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.5|Targets of second messengers] → [category|SW 3.5.2|Targets of c-di-GMP]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|general stress proteins (controlled by SigB)], [SW|membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|SigB regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    480,013 -> 480,864

    The protein

    [SW|Domains]

  • contains a C-terminal degenerated [SW|GGDEF domain] [Pubmed|23893111]
  • [SW|Cofactors]

  • binds c-di-GPM at high concentration (K(D) for c-di-GMP: 1.1 myM) [Pubmed|23893111]
  • [SW|Localization]

  • cell membrane, forms clusters at the cell poles and septa (with [SW|YdaM] and [SW|YdaN]) [Pubmed|27897378]
  • [SW|Interactions]

  • [SW|YdaK]-[SW|YdaM]-[SW|YdaN] [Pubmed|27897378]
  • Expression and Regulation

    Operon

  • ''[protein|search|ydaJ]-[protein|search|ydaK]-[protein|search|ydaL]-[protein|search|ydaM]-[protein|search|ydaN]'' [Pubmed|22383849]
  • [SW|Sigma factor]

  • [protein|search|SigB] [Pubmed|22383849]
  • Regulation

  • expressed during stress ([protein|search|SigB]) [Pubmed|22383849]
  • Biological materials

    Mutant

  • MGNA-C074 (ydaK::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2072 NBRP B. subtilis, Japan]
  • GP1592 (kan) available in [SW|Jörg Stülke]'s lab
  • References

  • 22383849,22821967,23893111,27897378