transcriptional activator of the acoA-acoB-acoC-acoL operon
function
regulation of acetoin utilization
product
transcriptional activator (for SigL-dependent promoter)
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.2|Utilization of acetoin][category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other][SW|Categories] containing this gene/protein
[SW|utilization of specific carbon sources], [SW|transcription factors and their control], [SW|sporulation proteins], [SW|Transcription factors activating transcription at SigL-dependent promoters]This gene is a member of the following [SW|regulons]
[SW|CcpA regulon]Gene
Coordinates on the chromosome (coding sequence)
883,758 -> 885,575
The protein
Protein family
[SW|Transcription factors activating transcription at SigL-dependent promoters]Expression and Regulation
Operon
''[protein|search|acoR]-[protein|search|sspH]'' [Pubmed|11274109][SW|Sigma factor]
[protein|search|SigA] [Pubmed|22900538]Regulation
repressed by glucose (3.7-fold) ([protein|search|CcpA]) [Pubmed|12850135]Regulatory mechanism
[protein|search|CcpA]: transcription repression [Pubmed|12850135]Biological materials
Mutant
1A912 ( ''acoR''::''kan''), [Pubmed|16585774], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A912&Search=1A912 BGSC] and in [SW|Jörg Stülke]'s labLabs working on this gene/protein
[SW|Michel Debarbouille], Pasteur Institute, Paris, France [http://www.pasteur.fr/ip/easysite/go/03b-00000m-0ob/recherche/departements-scientifiques/microbiologie/unites-et-groupes/unite-de-biologie-des-bacteries-pathogenes-a-gram-positif/les-membres-de-l-equipe Homepage]References
11274109,10368162,22900538,12850135,21906631 
