SubtiBank SubtiBank
greA [Wed Jul 13 2016 13:34:35 GMT+0200 (CEST)]
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greA [Wed Jul 13 2016 13:34:35 GMT+0200 (CEST)]

transcription elongation factor, resolves stalled RNA polymerase at promoter or promoter-proximal regions,
locus
BSU27320
pI
4.00
mw
17.00 kDa
function
transcription elongation
product
transcription elongation factor
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination] → [category|SW 3.1.5.6|Other proteins]
  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.9|Newly identified competence genes]
  • [category|SW 3|Information processing] → [category|SW 3.2|RNA synthesis and degradation] → [category|SW 3.2.1|Transcription] → [category|SW 3.2.1.3|Transcription elongation/ termination]
  • [SW|Categories] containing this gene/protein

  • [SW|transcription]
  • Gene

    Coordinates on the chromosome (coding sequence)
    2,791,494 -> 2,791,967

    Phenotypes of a mutant

  • [SW|RNA polymerase] accumulates in promoter-proximal regions of many genes [Pubmed|21515770]
  • The protein

    Protein family

  • greA/greB family (according to Swiss-Prot)
  • Structure

  • [PDB|1GRJ] (from ''E. coli'', 43% identity) [Pubmed|7854424]
  • [SW|Localization]

  • uniformly distributed throughout the nucleoid [Pubmed|16707701,21515770]
  • [SW|Interactions]

  • [protein|search|GreA]-[SW|RNA polymerase] [Pubmed|21515770]
  • Biological materials

    Mutant

  • BP351 (cm) available in [SW|Fabian Commichau]'s lab
  • References

    Reviews

  • 16815708,15720542,15294154,24763425
  • Original Publications

  • 16707701,21266474,21515770,23543716,7854424