L,D-transpeptidase involved in cell wall synthesis
function
cell wall biosynthesis
product
L,D-transpeptidase
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.1|Biosynthesis of peptidoglycan][category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.1|Biosynthesis of cell wall components] → [category|SW 2.6.1.1|Biosynthesis of peptidoglycan][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.1|Spore coat proteins] → [category|SW 4.2.1.1.8|Not yet assigned][SW|Categories] containing this gene/protein
[SW|cell wall synthesis], [SW|biosynthesis of cell wall components], [SW|sporulation proteins]This gene is a member of the following [SW|regulons]
[SW|CcpA regulon], [SW|SigK regulon]Gene
Coordinates on the chromosome (coding sequence)
1,476,518 -> 1,477,012
The protein
Paralogous protein(s)
[SW|YqjB][SW|Domains]
contains a N-terminal N-acetylglucosamine-polymer-binding [SW|LysM domain] [Pubmed|18430080]Structure
[PDB|1Y7M] [Pubmed|16287140][PDB|2MTZ] (complex with a peptidoglycan hexamuropeptide) [Pubmed|25429710][SW|Localization]
spore wall (according to Swiss-Prot)Expression and Regulation
Operon
''[protein|search|ykuE]-[protein|search|ldt]-[protein|search|ykuC]'' [Pubmed|22383849]''ldt'' [Pubmed|11011148][SW|Sigma factor]
[protein|search|SigK] [Pubmed|11011148]Regulation
repressed by glucose (3.3-fold) ([protein|search|CcpA]) [Pubmed|12850135]expressed during sporulation in the mother cell ([protein|search|SigK]) [Pubmed|11011148]Regulatory mechanism
[protein|search|CcpA]: transcription repression [Pubmed|12850135]References
Reviews
Original publications
12850135,11011148,17311917,22383849,22278298,22579252,16287140,25429710 
