SubtiBank SubtiBank
ppiB
SAVE THE DATE! 21st International Conference on Bacilli and Gram-Positive Bacteria. Prague, Czech Republic, June 7-11, 2021.

ppiB

peptidyl-prolyl isomerase
locus
BSU_23360
pI
5.47
mw
15.11 kDa
protein length
143 aa Sequence Blast
gene length
432 bp Sequence Blast
function
protein folding
product
peptidyl-prolyl isomerase
essential
no
ec
5.2.1.8
synonyms
cypBS

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.2|Chaperones/ protein folding]
  • Gene

    Coordinates
    2,435,360 2,435,791

    The protein

    Catalyzed reaction/ biological activity

  • [protein]-peptidylproline (ω=180) --> [protein]-peptidylproline (ω=0) (according to UniProt)
  • Protein family

  • cyclophilin-type PPIase family (single member, according to UniProt)
  • [SW|Domains]

  • PPIase cyclophilin-type domain (aa 1-143) (according to UniProt)
  • Structure

  • [PDB|2MVZ] (from Geobacillus kaustophilus, 75% identity) [pubmed|25923019]
  • Expression and Regulation

    Operons

    genes
    [gene|6D38B333DE44EB903E151004BA30F3361CC1BE7C|ppiB]
    description
    [Pubmed|8022278]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|8022278], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]
  • view in new tab

    Biological materials

    Mutant

  • BKE23360 ([gene|6D38B333DE44EB903E151004BA30F3361CC1BE7C|ppiB]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE23360 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATTGTATGCCTACTTTCT, downstream forward: _UP4_TAATCGGCAGGCAAAAGGCT
  • BKK23360 ([gene|6D38B333DE44EB903E151004BA30F3361CC1BE7C|ppiB]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK23360 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATTGTATGCCTACTTTCT, downstream forward: _UP4_TAATCGGCAGGCAAAAGGCT
  • References

  • 9748346,1516692,9297832,8639516,8022278,25923019