SubtiBank SubtiBank
yxjM
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yxjM

two-component sensor kinase
locus
BSU_38900
pI
6.80
mw
45.07 kDa
protein length
406 aa Sequence Blast
gene length
1221 bp Sequence Blast
function
unknown
product
two-component sensor kinase ([SW|NarL family])
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.2|Protein kinases]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.2|Control of two-component response regulators] → [category|SW 3.4.2.2.1|Two-component sensor kinase]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.4|Phosphorylation on a His residue]

    • Gene

    Coordinates
    3,993,162 3,994,382

    The protein

    Catalyzed reaction/ biological activity

  • autophosphorylation, phosphorylation of [protein|23F365C23BDEE02D42C9355FC7D2A65DAF9F79ED|YxjL]
  • ATP + protein L-histidine --> ADP + protein N-phospho-L-histidine (according to UniProt)

    • [SW|Domains]

  • [SW|Histidine kinase domain] (aa 209-396) (according to UniProt)

    • Modification

  • autophosphorylation on a His residue

    • [SW|Localization]

  • cell membrane (according to UniProt)

    • Biological materials

    Mutant

  • MGNA-B801 (yxjM::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1800 NBRP B. subtilis, Japan]
  • BKE38900 ([gene|6D10C9232F0D28973F7C3C6ECDFD6948928CB23F|yxjM]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE38900 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GTTCATGCTGGTCCTTCTTT, downstream forward: _UP4_ATGACAACGAATAAGGAGCA
  • BKK38900 ([gene|6D10C9232F0D28973F7C3C6ECDFD6948928CB23F|yxjM]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK38900 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GTTCATGCTGGTCCTTCTTT, downstream forward: _UP4_ATGACAACGAATAAGGAGCA

    • References

  • 10094672