sublancin S-glycosyltransferase
function
biosynthesis of the antimicrobial peptide sublancin
product
sublancin S-glycosyltransferase
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.6|Miscellaneous metabolic pathways] → [category|SW 2.6.6.1|Biosynthesis of antibacterial compounds][category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.8|Protein modification/ other][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.15|Biosynthesis of antibacterial compounds][category|SW 5|Prophages and mobile genetic elements] → [category|SW 5.1|Prophages] → [category|SW 5.1.2|SP-beta prophage][SW|Categories] containing this gene/protein
[SW|SP-beta prophage], [SW|membrane proteins], [SW|protein modification], [SW|biosynthesis of antibacterial compounds]This gene is a member of the following [SW|regulons]
[SW|Abh regulon], [SW|AbrB regulon], [SW|Rok regulon], [SW|YvrHb regulon]Gene
Coordinates on the chromosome (coding sequence)
2,265,668 -> 2,266,936
The protein
Catalyzed reaction/ biological activity
selectively modifies Cys22 in a 56-amino acid peptide substrate [protein|search|SunA] and can accept a variety of NDP-sugars [Pubmed|21196935]Protein family
EngA subfamily (according to Swiss-Prot)[SW|Localization]
cell membrane (according to Swiss-Prot)Expression and Regulation
Operon
''[protein|search|sunT]-[protein|search|bdbA]-[protein|search|sunS]-[protein|search|bdbB]'' [Pubmed|16306698]''[SW|sunA]-[SW|sunT]-[SW|bdbA]-[SW|sunS]-[SW|bdbB]'' [Pubmed|22383849]Regulation
repressed by [protein|search|Rok]-[SW|DnaA] [Pubmed|27902860,15743949]Regulatory mechanism
activated by [SW|YvrHb] [Pubmed|16306698][protein|search|Rok]-[SW|DnaA]: transcription repression [Pubmed|27902860,15743949][protein|search|AbrB]: transcription repression[Pubmed|20817675][protein|search|Abh]: transcription activation [Pubmed|20817675]Additional information
the amount of the mRNA is substantially decreased upon depletion of [Rny|search|RNase Y] [PubMed|21815947]References
27902860,15743949,21196935,20817675,21910430,21815947 
