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fliW [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]
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fliW [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

checkpoint protein for hag expression, CsrA anatagonist
locus
BSU35380
pI
4.00
mw
16.00 kDa
function
control of CsrA activity
product
flagellar assembly factor, CsrA anatagonist
essential
no
synonyms
yviF

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.1|Motility and chemotaxis] → [category|SW 4.1.1.2|Flagellar proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|motility and chemotaxis]
  • This gene is a member of the following [SW|regulons]

  • [SW|SigD regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,636,264 -> 3,636,695

    The protein

    Catalyzed reaction/ biological activity

  • [protein|search|FliW] binds [protein|search|CsrA] when [protein|search|Hag] is secreted after hook completion (and [protein|search|FliW] released from the [protein|search|Hag]-[protein|search|FliW] complex) to allow translation of the'' [protein|search|hag]'' mRNA [Pubmed|21895793]
  • Protein family

  • fliW family (according to Swiss-Prot)
  • Structure

  • [PDB|5DMD] (from ''Geobacillus thermodenitrificans'') [Pubmed|27551070]
  • [PDB|5DMB] ([SW|FliW]-[SW|CsrA] complex) [Pubmed|27551070]
  • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)
  • [SW|Interactions]

  • [protein|search|FliW]-[protein|search|Hag] [Pubmed|21895793]
  • [protein|search|FliW]-[protein|search|CsrA] [Pubmed|21895793,27516547]
  • Additional information

  • [protein|search|CsrA] and [protein|search|FliW] form a conserved module in many bacteria [Pubmed|21895793,27516547]
  • Expression and Regulation

    [SW|Sigma factor]

  • [SW|SigD] [Pubmed|26577401]
  • References

    Reviews

  • 22672726,25251856
  • Original Publications

  • 16936039,23144244,21895793,26577401,27516547,27551070