SubtiBank SubtiBank
yisV
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yisV

similar to transcriptional regulator ([SW|MocR/ GabR family])
locus
BSU_10880
pI
9.30
mw
54.11 kDa
protein length
484 aa Sequence Blast
gene length
1455 bp Sequence Blast
function
unknown
product
unknown
essential
no
synonyms
yisW

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.6|Transcription factor/ other/ based on similarity]
  • Gene

    Coordinates
    1,166,737 1,168,191

    The protein

    Protein family

  • [SW|MocR/ GabR family] [Pubmed|22020104]
  • [SW|class-I pyridoxal-phosphate-dependent aminotransferase family] (according to UniProt)
  • Paralogous protein(s)

  • [protein|B1A95EAE40AFA40BF12EE9B41287921417A39562|YdfD]
  • [SW|Domains]

  • N-terminal DNA-binding helix-turn-helix motif; C-terminal domain is homologous to PLP-binding large domain of aminotransferases.
  • [SW|HTH gntR-type domain] (aa 14-82) (according to UniProt)
  • [SW|Cofactors]

  • PLP
  • Structure

  • [PDB|1WST] (aminotransferase from Thermococcus profundus, 29% identity)
  • Expression and Regulation

    Operons

    genes
    [gene|6A3F08CD939CCDEC1F784D658B815A6D0E1AAC3D|yisV]
    description
    [pubmed|22383849]
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    Biological materials

    Mutant

  • MGNA-B211 (yisW::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1210 NBRP B. subtilis, Japan]
  • BKE10880 ([gene|6A3F08CD939CCDEC1F784D658B815A6D0E1AAC3D|yisV]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE10880 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGCCCCCCTTTTTTACAC, downstream forward: _UP4_CGCCTGATGATGTCCTAGGC
  • BKK10880 ([gene|6A3F08CD939CCDEC1F784D658B815A6D0E1AAC3D|yisV]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK10880 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGCCCCCCTTTTTTACAC, downstream forward: _UP4_CGCCTGATGATGTCCTAGGC
  • References

  • 11756427,22020104