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ytrA [Tue Dec 13 2016 11:16:35 GMT+0100 (CET)]
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ytrA [Tue Dec 13 2016 11:16:35 GMT+0100 (CET)]

transcriptional repressor, GntR family, control of cell envelope stress responses in response to ramoplanin
locus
BSU30460
pI
8.09
mw
14.00 kDa
function
control of cell envelope stress responses
product
transcriptional repressor (GntR family)
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.9|Newly identified competence genes]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.3|Sporulation/ other]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.13|Resistance against toxins/ antibiotics]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.5|Cold stress proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|transcription factors and their control], [SW|cold stress proteins], [SW|resistance against toxins/ antibiotics]
  • This gene is a member of the following [SW|regulons]

  • [SW|YtrA regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,118,847 -> 3,119,239

    The protein

    Protein family

  • [SW|GntR family] of transcription factors
  • Structure

  • [PDB|3NEU] (similar protein from ''Listeria innocua'', 41% identity)
  • Expression and Regulation

    Operon

  • ''[protein|search|ytrG]-[protein|search|ytrA]-[protein|search|ytrB]-[protein|search|ytrC]-[protein|search|ytrD]-[protein|search|ytrE]-[protein|search|ytrF]'' [Pubmed|10986249,21856850]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|10986249]
  • Regulation

  • induced by ramoplanin ([protein|search|YtrA]) [Pubmed|21856850]
  • expressed early in the stationary phase [Pubmed|10986249]
  • induced by cold shock (5-fold) [Pubmed|12399512]
  • Regulatory mechanism

  • [protein|search|YtrA]: transcription repression [Pubmed|10986249,21856850]
  • References

  • 10986249,12399512,23504016,21856850