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yojI
similar to multidrug efflux transporters
product
putative multidrug exporter
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.15|Multidrug exporters/ based on homology][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.14|Resistance against toxins/ antibiotics/ based on similarity][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]Gene
Coordinates
2,119,393 2,120,751
The protein
Protein family
[SW|MOP exporter family][SW|multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family] (according to UniProt)Structure
[PDB|3MKT] (multidrug exporter from Vibrio cholerae, 37% identity) [pubmed|20861838][SW|Localization]
cell membrane (according to UniProt)Expression and Regulation
Operons
genes
[gene|692C2F92DBE9E917697A883DA66C6E0FA2DE3FBA|yojI]-[gene|5EEEDE60CE9E5CDAEBAB0E03AABDF1DF62F1F002|rsbRC]
description
[Pubmed|22383849]
view in new tabBiological materials
Mutant
MGNA-B427 (yojI::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1426 NBRP B. subtilis, Japan]BKE19440 ([gene|692C2F92DBE9E917697A883DA66C6E0FA2DE3FBA|yojI]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE19440 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATACATTGATCTCCGTTTC, downstream forward: _UP4_CACATTTAAAAGAGGTGATCBKK19440 ([gene|692C2F92DBE9E917697A883DA66C6E0FA2DE3FBA|yojI]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK19440 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATACATTGATCTCCGTTTC, downstream forward: _UP4_CACATTTAAAAGAGGTGATCReferences