SubtiBank SubtiBank
ftsA [Mon Aug 31 2015 13:54:11 GMT+0200 (CEST)]
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ftsA [Mon Aug 31 2015 13:54:11 GMT+0200 (CEST)]

cell division protein, membrane anchor for FtsZ
locus
BSU15280
pI
5.00
mw
47.00 kDa
function
formation of Z-ring
product
cell division protein
essential
no
synonyms
spoIIN

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.8|Cell division] → [category|SW 1.1.8.2|Other genes]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|cell division], [SW|membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|SigH regulon], [SW|WalR regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    1,596,474 -> 1,597,796

    Phenotypes of a mutant

  • cells become elongated [Pubmed|24218584]
  • the ''[protein|search|ftsA]'' mutation is synthetically lethal with a ''[protein|search|sepF]'' mutation [Pubmed|24218584]
  • The protein

    Protein family

  • ftsA/mreB family (according to Swiss-Prot)
  • [SW|Localization]

  • septal at the cell membrane [Pubmed|20566861]
  • septal localization depends on the proton motive force [Pubmed|20566861]
  • [SW|Interactions]

  • [protein|search|FtsZ]-[protein|search|FtsA] [Pubmed|16159787]
  • [protein|search|PlsX]-[protein|search|FtsA] [Pubmed|24224907]
  • Expression and Regulation

    Operon

  • ''[protein|search|ftsA]-[protein|search|ftsZ]'' [Pubmed|1569582]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|1569582], [protein|search|SigH] [Pubmed|1569582]
  • Regulation

  • activated by [protein|search|WalR] [Pubmed|10878122]
  • Biological materials

    Mutant

  • 1A787 ( ''ftsA''::''cat''), [Pubmed|8071208], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A787&Search=1A787 BGSC]
  • References

    Reviews

  • 19680248
  • Original Publications

  • 16796675,12081956,16159787,11298280,18776011,9287012,1569582,10878122,7592498,20566861,23036588,23701187,24218584,24224907,24316672