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kre [Tue Dec 13 2016 11:16:32 GMT+0100 (CET)]
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kre [Tue Dec 13 2016 11:16:32 GMT+0100 (CET)]

ComK repressor, stimulates degradation of the comK mRNA
locus
BSU14020
pI
10.00
mw
17.00 kDa
function
control of ComK accumulation and of bistable competence gene expression
product
ComK repressor
essential
no
synonyms
ykyB

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.7|Genetic competence]
  • [category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.3|Genetic competence]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.1|Phosphorylation on an Arg residue]
  • [SW|Categories] containing this gene/protein

  • [SW|genetic competence]
  • This gene is a member of the following [SW|regulons]

  • [SW|ComK regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    1,474,560 -> 1,475,024

    The protein

    Catalyzed reaction/ biological activity

  • stimulates [SW|ComK] mRNA degradation [Pubmed|26110430]
  • controls stability of several mRNAs (see [SW|Kre regulon]) [Pubmed|26110430]
  • [SW|Localization]

  • cytoplasm [Pubmed|26110430]
  • Expression and Regulation

    Operon

  • ''[protein|search|kre]'' [Pubmed|8169223]
  • Regulation

  • repressed in competent cells ([SW|ComK]) [Pubmed|26110430]
  • Regulatory mechanism

  • [SW|ComK]: transcription repression [Pubmed|26110430]
  • Biological materials

    Mutant

  • MGNA-A764 (ykyB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/764 NBRP B. subtilis, Japan]
  • References

    Reviews

  • 26110607
  • Original Publications

  • 8169223,26110430