SubtiBank SubtiBank
sigO [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

sigO [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

RNA polymerase sigma factor SigO (with RsoA)
locus
BSU33230
pI
9.00
mw
20.00 kDa
function
RNA polymerase sigma factor
product
co-sigma factor with RsoA
essential
no
synonyms
yvrI

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.2|RNA synthesis and degradation] → [category|SW 3.2.1|Transcription] → [category|SW 3.2.1.2|Sigma factors]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.1|Sigma factors]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.3|Acid stress proteins (controlled by YvrI-YvrHa)]
  • [SW|Categories] containing this gene/protein

  • [SW|transcription], [SW|sigma factors and their control], [SW|acid stress proteins (controlled by SigO-RsoA)]
  • This gene is a member of the following [SW|regulons]

  • [SW|YvrHb regulon], [SW|SigO-RsoA regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,409,462 -> 3,409,992

    The protein

    [SW|Domains]

  • contains a DNA-binding helix-turn-helix motif (HTH) and the region 4.2 of Sigma factors [Pubmed|19940246]
  • [SW|Interactions]

  • [protein|search|SigO]-[protein|search|RpoB] [Pubmed|19940246]
  • [protein|search|SigO]-[SW|RsoA] [Pubmed|19940246]
  • [SW|RsiO]-[SW|SigO], at neutral pH, to inhibit [SW|SigO] activity [Pubmed|26651345]
  • Expression and Regulation

    Operon

  • ''[protein|search|sigO]-[SW|rsoA]'' [Pubmed|19047353]
  • [SW|Sigma factor]

  • [protein|search|SigO]-[SW|RsoA] [Pubmed|19047353]
  • Regulation

  • induced by acidic growth conditions [Pubmed|19047353]
  • Regulatory mechanism

  • activated by [SW|YvrHb] [Pubmed|16306698]
  • Labs working on this gene/protein

  • [SW|John Helmann], Cornell University, USA [http://www.micro.cornell.edu/research/labs/helmann-lab/index.cfm Homepage]
  • References

  • 18573182,19047353,26651345,16306698,19940246,26367498,26400263,27558998