SubtiBank SubtiBank
rodZ [Tue Dec 13 2016 11:16:33 GMT+0100 (CET)]
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

rodZ [Tue Dec 13 2016 11:16:33 GMT+0100 (CET)]

required for cell shape determination
locus
BSU16910
pI
4.00
mw
23.00 kDa
function
required for cell shape determination
product
morphogenic protein
essential
yes
synonyms
ymfM

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.2|Cell shape]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.3|Sporulation/ other]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|cell shape], [SW|membrane proteins], [SW|sporulation/ other], [SW|essential genes]
  • Gene

    Coordinates on the chromosome (coding sequence)
    1,761,707 -> 1,762,573

    Phenotypes of a mutant

  • essential [Pubmed|19164570,23879732]
  • depletion results in the formation of shorter and rounder cells [Pubmed|23879732]
  • depletion results in disturbed formation of asymmetric septa and perturbed [SW|SigF] activation [Pubmed|27415800]
  • hypersensitivity to sorbic acid stress [Pubmed|27818647]
  • The protein

    [SW|Domains]

  • N-terminal cytoplasmic domain (RodZn), a transmembrane domain, and C-terminal extra-cytoplasmic domain (RodZc) [Pubmed|25503291]
  • [SW|Localization]

  • membrane protein (according to Swiss Prot)
  • [SW|Interactions]

  • part of the [SW|cell wall biosynthetic complex] [Pubmed|21636744,21636745]
  • [protein|search|RodZ]-[protein|search|MreD] [Pubmed|23879732]
  • [protein|search|RodZ]-[protein|search|MreB] [Pubmed|23879732]
  • [protein|search|RodZ]-[SW|MreBH] [Pubmed|23879732]
  • [protein|search|RodZ]-[protein|search|Mbl] [Pubmed|23879732]
  • [SW|SpoIIE]-[SW|RodZ] [Pubmed|27415800]
  • Additional information

  • overexpression results in growth inhibition in minimal medium (in the absence of Mg2 ) [Pubmed|19164570]
  • RodZ is destabilized in a ''[protein|search|mreB]'' mutant [Pubmed|23879732]
  • Labs working on this gene/protein

  • [SW|Adriano Henriques], Lisbon, Portugal [http://www.itqb.unl.pt/research/biology/microbial-development homepage]
  • References

  • 19164570,21636744,21636745,23879732,25503291,27415800,27818647