SubtiBank SubtiBank
yhxC
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yhxC

similar to alcohol dehydrogenase
locus
BSU_10400
pI
7.26
mw
30.69 kDa
protein length
285 aa Sequence Blast
gene length
858 bp Sequence Blast
function
unknown
product
unknown
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.7|Genetic competence]
  • [category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.3|Genetic competence]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
  • [category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]
  • Gene

    Coordinates
    1,115,698 1,116,555

    Phenotypes of a mutant

  • reduced transfomation efficiency [pubmed|32249531]
  • The protein

    Protein family

  • [SW|Short-chain dehydrogenases/reductases (SDR) family] (according to UniProt)
  • Paralogous protein(s)

  • [protein|0DD474462720CAEE2AE17017BD7CA385238EBC6F|YxbG], [protein|20A7DBA142F3BF8DCAD9732BD908CE8CC79AA993|BacC], [protein|248F0805272FED9B38ECBB31E2872BC9EC163CE0|YmfI], [protein|439B468A13137000FB42E9389391CB4986FFED84|FabG]
  • [protein|6BA346D8A7B496F9618AFAB4FEEF4BD1A41D2C7E|YoxD]:
  • [protein|739B228743BC1FE9E6888E999BC0E4F615E36F9E|YhxD]:
  • [protein|B6FF689E65906186F3576B378650D713DB84EDDA|YcdF]:
  • [protein|CA4597C6253CCF7D7954686A30AF041808BDF8E5|Gdh]:
  • [protein|CE990D33A12C50D22506A52E0099F7D97A762D4E|FadH]:
  • [protein|D9D1FCBFC62F93CAA34DF61A784406F4E9EE6768|YjdA]:
  • [protein|EAEEA4DD9641919830A81185333A2610B964D37C|YhdF]:
  • [protein|FBBDE1E058223D5E8CEB07CAA50940A329C809E4|KduD]:
  • [protein|3161519994609DA9360ED6E073E4A4C8C6210EFB|YdaD]:
  • [protein|4DEFC2998464BF8327578C36A13A10DD277F991E|YkvO]:
  • [protein|0DD474462720CAEE2AE17017BD7CA385238EBC6F|YxbG] (36,2%), [protein|439B468A13137000FB42E9389391CB4986FFED84|FabG] (34.7%), [protein|B6FF689E65906186F3576B378650D713DB84EDDA|YcdF] (32,4%),
  • [protein|CA4597C6253CCF7D7954686A30AF041808BDF8E5|Gdh] (34,1%), [protein|20A7DBA142F3BF8DCAD9732BD908CE8CC79AA993|BacC] (36.0%), [protein|248F0805272FED9B38ECBB31E2872BC9EC163CE0|YmfI](30.3%), [protein|CE990D33A12C50D22506A52E0099F7D97A762D4E|FadH] (31.9%), [protein|FBBDE1E058223D5E8CEB07CAA50940A329C809E4|KduD](33,6%), [protein|4DEFC2998464BF8327578C36A13A10DD277F991E|YkvO] (35.2%), [protein|6BA346D8A7B496F9618AFAB4FEEF4BD1A41D2C7E|YoxD] (31,5%), [protein|D9D1FCBFC62F93CAA34DF61A784406F4E9EE6768|YjdA] (32,9%)
  • Structure

  • [PDB|3I30] (from ''Bacillus Anthracis Str. 'amesAncestor''', 68% identity)
  • Expression and Regulation

    Operons

    genes
    [gene|6047F2493FCE3D2A9BDB1AD88E5926ECEED81036|yhxC]
    description
    [Pubmed|8196543]

    sigma factors

  • [protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE]: sigma factor, [Pubmed|15699190,12480901], in [regulon|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE regulon]
  • regulation

  • expressed during sporulation in the mother cell ([protein|search|SigE]) [Pubmed|15699190,12480901]
  • view in new tab

    Biological materials

    Mutant

  • MGNA-A718 (yhxC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/718 NBRP B. subtilis, Japan]
  • BKE10400 ([gene|6047F2493FCE3D2A9BDB1AD88E5926ECEED81036|yhxC]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE10400 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATGAAATCACTCCTTTTC, downstream forward: _UP4_TAATAAAAAGCCAATCCTTG
  • BKK10400 ([gene|6047F2493FCE3D2A9BDB1AD88E5926ECEED81036|yhxC]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK10400 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATGAAATCACTCCTTTTC, downstream forward: _UP4_TAATAAAAAGCCAATCCTTG
  • References

  • 15699190,12480901,8196543,32249531