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gerAB [Fri Jun 24 2016 17:44:59 GMT+0200 (CEST)]
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gerAB [Fri Jun 24 2016 17:44:59 GMT+0200 (CEST)]

nutrient receptor, germination response to L-alanine
locus
BSU33060
pI
9.00
mw
41.00 kDa
function
germination response to L-alanine
product
nutrient receptor
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.1|Amino acid transporters] → [category|SW 1.2.4.1.4|APC superfamily]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.4|Germination] → [category|SW 4.2.4.1|Germinant receptors]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|germination], [SW|membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|SigF regulon], [SW|SigG regulon], [SW|SpoVT regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,392,199 -> 3,393,296

    The protein

    Paralogous protein(s)

  • [SW|GerBB], [SW|GerKB], [protein|search|YndE]
  • [SW|Localization]

  • predicted to be an integral membrane protein with ten membrane-spanning helices [Pubmed|21378181]
  • inner spore membrane [Pubmed|26731423]
  • [SW|Interactions]

  • [SW|GerAA]-[SW|GerAB]-[SW|GerAC] (tentative receptor complex) [Pubmed|21378181,21378197]
  • [SW|GerAB] is part of the [SW|germinosome] in the spore inner membrane [Pubmed|21696470]
  • Expression and Regulation

    Operon

  • ''[SW|gerAA]-[SW|gerAB]-[SW|gerAC]'' [Pubmed|3110007]
  • [SW|Sigma factor]

  • [protein|search|SigG] [Pubmed|15699190], [protein|search|SigF] [Pubmed|16497325]
  • Regulation

  • expressed during sporulation in the forespore ([protein|search|SigF], [protein|search|SigG], [SW|SpoVT]) [Pubmed|16497325,15699190,8755877]
  • expression level depends on sporulation conditions (medim composition, temperature) [Pubmed|22327596]
  • Regulatory mechanism

  • [SW|SpoVT]: transcription repression [Pubmed|8755877]
  • References

  • 3110007,17573930,12670969,2110996,15774895,16497325,16352818,8755877,21378181,21378197,21696470,22327596,23396907,24916603,22343299,16740944,26731423