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ansB [Mon Aug 31 2015 13:55:25 GMT+0200 (CEST)]
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ansB [Mon Aug 31 2015 13:55:25 GMT+0200 (CEST)]

L-aspartase
locus
BSU23570
pI
5.69
mw
52.00 kDa
function
aspartate degradation
product
L-aspartase
essential
no
ec
4.3.1.1
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.2|Utilization of amino acids] → [category|SW 2.3.2.6|Utilization of asparagine/ aspartate]

    • [SW|Categories] containing this gene/protein

  • [SW|utilization of amino acids], [SW|membrane proteins]

    • This gene is a member of the following [SW|regulons]

  • [SW|AnsR regulon]

    • The protein

    Catalyzed reaction/ biological activity

  • L-aspartate = fumarate + NH3 (according to Swiss-Prot)

    • Protein family

  • Aspartase subfamily (according to Swiss-Prot)

    • Paralogous protein(s)

  • [protein|search|CitG]

    • Structure

  • [PDB|3R6Q] (from ''Bacillus'' sp. YM55-1, 72% identity, 92% similarity) [Pubmed|21661762]

    • [SW|Localization]

  • cell membrane (according to Swiss-Prot)

    • Expression and Regulation

    Operon

  • ''[protein|search|ansA]-[protein|search|ansB]'' [Pubmed|1711029]
  • ''[protein|search|ansA]-[protein|search|ansB]-[protein|search|mleN]-[protein|search|mleA]'' [Pubmed|22383849]

    • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|1711029]

    • Regulation

  • expressed in the presence of asparagine ([protein|search|AnsR]) [Pubmed|11914346]

    • Regulatory mechanism

  • [protein|search|AnsR]: transcription repression [Pubmed|11914346]

    • Biological materials

    Mutant

  • GP1153 (del ''ansAB''::''ermC'') available in the [SW|Stülke] lab

    • References

  • 8478318,1711029,1711029,11914346,21219666,22383849