yngI [Tue Dec 13 2016 11:16:33 GMT+0100 (CET)]

aceto-acetyl-CoA ligase, may be involved in surfactin production

locus: BSU18250

pI: 5.98

mw: 61.00 kDa

function: mother cell metabolism, leucine utilization

product: aceto-acetyl-CoA ligase

essential: no

ec: 6.2.1.16

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.2|Utilization of amino acids] → [category|SW 2.3.2.9|Utilization of branched-chain amino acids]
• [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]

[SW|Categories] containing this gene/protein

• [SW|utilization of amino acids], [SW|sporulation proteins]

This gene is a member of the following [SW|regulons]

• [SW|SigE regulon]

Gene

Coordinates on the chromosome (coding sequence): 1,954,525 -> 1,956,174

The protein

Catalyzed reaction/ biological activity

• ATP + acetoacetate + CoA <=> AMP + diphosphate + acetoacetyl-CoA [Pubmed|19935659]

Paralogous protein(s)

• [protein|search|LcfA], [protein|search|LcfB], [protein|search|YhfT]

Expression and Regulation

Operon

• ''[protein|search|yngJ]-[protein|search|yngI]-[protein|search|yngH]-[SW|yngHB]-[protein|search|yngG]-[protein|search|yngF]-[protein|search|yngE]'' [Pubmed|12662922]

[SW|Sigma factor]

• [protein|search|SigE] [Pubmed|15699190,12662922]

Regulation

• expressed during sporulation in the mother cell ([protein|search|SigE]) [Pubmed|15699190,12662922]

Biological materials

Mutant

• available in [SW|Mohamed Marahiel]'s lab [Pubmed|20797616]

References

• 15699190,12662922,19935659,20797616