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sigG [Mon Aug 31 2015 13:54:11 GMT+0200 (CEST)]
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sigG [Mon Aug 31 2015 13:54:11 GMT+0200 (CEST)]

RNA polymerase sporulation forespore-specific (late) sigma factor SigG
locus
BSU15330
pI
5.50
mw
29.00 kDa
function
transcription of sporulation genes (late forespore)
product
RNA polymerase sporulation forespore-specific
(late) sigma factor SigG
essential
no
synonyms
spoIIIG

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.2|RNA synthesis and degradation] → [category|SW 3.2.1|Transcription] → [category|SW 3.2.1.2|Sigma factors]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.1|Sigma factors]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
  • syns
    spoIIIG

    [SW|Categories] containing this gene/protein

  • [SW|transcription], [SW|sigma factors and their control], [SW|sporulation proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|AbrB regulon], [SW|SigF regulon], [SW|SigG regulon], [SW|SinR regulon], [SW|Spo0A regulon]
  • The protein

    Protein family

  • sigma-70 factor family (according to Swiss-Prot)
  • Paralogous protein(s)

  • [protein|search|SigF]
  • Effectors of protein activity

  • [protein|search|Gin] inhibits SigG activity [Pubmed|19497328]
  • the activity of [protein|search|SigG]-containing [SW|RNA polymerase] is modulated by [protein|search|YlyA] [Pubmed|23678950]
  • [SW|Interactions]

  • [protein|search|SigG]-[protein|search|RpoB]-[protein|search|RpoC]
  • [protein|search|CsfB]-[protein|search|SigG] [Pubmed|25835496,19497328]
  • [SW|SpoIIAB]-[protein|search|SigG] [Pubmed|8885263]
  • Expression and Regulation

    Operon

  • ''[SW|spoIIGA]-[protein|search|sigE]-[protein|search|sigG]'' [Pubmed|1902213]
  • ''[protein|search|sigG]'' [Pubmed|1902213]
  • [SW|Sigma factor]

  • ''[SW|spoIIGA]'': [protein|search|SigA] [Pubmed|2512576]
  • ''[protein|search|sigG]'': [protein|search|SigF], [protein|search|SigG] [Pubmed|1902213]
  • Regulation

  • ''[SW|spoIIGA]'': expressed under conditions that trigger sporulation ([SW|Spo0A]) [http://www.ncbi.nlm.nih.gov/sites/entrez/8288522,15687200 PubMed]
  • ''[protein|search|sigG]'': expressed during sporulation ([protein|search|SigF], [protein|search|SigG]) [Pubmed|1902213]
  • the mRNA accumulates in a ''[protein|search|ymdB]'' mutant [Pubmed|24163345]
  • Regulatory mechanism

  • repression by [protein|search|SinR]
  • [SW|Spo0A]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/8288522,15687200 PubMed]
  • [protein|search|AbrB]: transcription repression [Pubmed|20817675]
  • Labs working on this gene/protein

  • [SW|Charles Moran], Emory University, NC, USA [http://www.microbiology.emory.edu/moran_c.html homepage]
  • References

    Reviews

  • 20833318
  • The [SW|SigG regulon]

  • 16497325
  • Original Publications

  • 1900507,1902463,15175314,10806362,1902213,2497051,12867473,16707705,9829949,1487728,2448286,9852018,19497328,8126438,8355618,24163345,18820020,2493633,7961403,15256570,12813085,9004507,8885263,18485064,19390092,23678950,22984259,20817675,21935351,25835496