SEDS family peptidoglycan glycosyltransferase, required for spore cortex peptidoglycan synthesis
function
spore cortex peptidoglycan synthesis
product
SEDS family peptidoglycan glycosyltransferase
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.1|Biosynthesis of peptidoglycan][category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.1|Biosynthesis of cell wall components] → [category|SW 2.6.1.1|Biosynthesis of peptidoglycan][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|cell wall synthesis], [SW|biosynthesis of cell wall components], [SW|sporulation proteins], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|SigE regulon], [SW|SpoIIID regulon]Gene
Coordinates on the chromosome (coding sequence)
1,590,317 -> 1,591,417
The protein
Protein family
ftsW/rodA/spoVE family (according to Swiss-Prot) SEDS proteins (shape, elongation, division, and sporulation)Paralogous protein(s)
[protein|search|FtsW], [protein|search|RodA][SW|Localization]
integral membrane protein, forespore [Pubmed|17981970][SW|Interactions]
[SW|SpoVD]-[SW|SpoVE] [Pubmed|20417640], this protects [SW|SpoVE] from proteolytic degradation [Pubmed|20417640]Expression and Regulation
Operon
''[protein|search|murE]-[protein|search|mraY]-[protein|search|murD]-[SW|spoVE]-[protein|search|murG]-[protein|search|murB]-[SW|divIB]-[protein|search|ylxW]-[protein|search|ylxX]-[protein|search|sbp]'' [Pubmed|1391053]''[SW|spoVE]-[protein|search|murG]-[protein|search|murB]-[SW|divIB]-[protein|search|ylxW]-[protein|search|ylxX]-[protein|search|sbp]'' [Pubmed|1391053]''[SW|spoVE]'' [Pubmed|1391053][SW|Sigma factor]
''[SW|spoVE]'': [protein|search|SigE] [Pubmed|8320223]Regulation
expressed during vegatative growth, then switched off, and again expressed during sporulation in the mother cell ([protein|search|SigE]) [Pubmed|1391053]Regulatory mechanism
[SW|SpoIIID]: transcription repression [Pubmed|15383836]Additional information
the mRNA is cleaved by [rnc|search|RNase III] [PubMed|26883633]References
20417640,17981970,8320223,1391053,15383836,26883633,27525505 
