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hisI [Tue Oct 25 2016 16:58:52 GMT+0200 (CEST)]
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hisI [Tue Oct 25 2016 16:58:52 GMT+0200 (CEST)]

phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase
locus
BSU34860
pI
4.00
mw
23.00 kDa
function
biosynthesis of histidine
product
phosphoribosyl-AMP cyclohydrolase /
phosphoribosyl-ATP pyrophosphohydrolase
essential
no
ec
3.5.4.19
synonyms
hisIE
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.14|Biosynthesis/ acquisition of histidine]

    • [SW|Categories] containing this gene/protein

  • [SW|biosynthesis/ acquisition of amino acids]

    • Gene

    Coordinates on the chromosome (coding sequence)
    3,582,936 -> 3,583,565

    The protein

    Catalyzed reaction/ biological activity

  • 1-(5-phosphoribosyl)-ATP H2O = 1-(5-phosphoribosyl)-AMP diphosphate (according to Swiss-Prot)

    • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)

    • Expression and Regulation

    Operon

  • ''[protein|search|hisZ]-[protein|search|hisG]-[protein|search|hisD]-[protein|search|hisB]-[protein|search|hisH]-[protein|search|hisA]-[protein|search|hisF]-[protein|search|hisI]'' [Pubmed|12107147]

    • Regulation

  • repressed by casamino acids [Pubmed|12107147]

    • References

  • 12107147