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ssrA [2020-09-10 09:28:33]
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ssrA [2020-09-10 09:28:33]

tmRNA
locus
BSU_misc_RNA_55
pI
0.00
mw
0.00 kDa
function
trans-translation
product
tmRNA
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.12|Translation/ other]
  • [category|SW 6|Groups of genes] → [category|SW 6.9|NcRNA] → [category|SW 6.9.2|tmRNA]
  • Gene

    Phenotypes of a mutant

  • essential in the absence of [protein|F7F780D11A6B11EB62CFA5202D1243A381AB40E1|BrfA] [https://www.biorxiv.org/content/biorxiv/early/2019/08/15/732420.full.pdf reference]
  • The protein

    Structure

  • [PDB|1P6V] (from ''Aquifex aeolicus'', the tRNA domain of [protein|5C12BB19B975F7FEBCFA119DAC66338C20FCECFA|SsrA] in complex with [protein|D19519B5A776D6E8EC2BFE7A7D67469CA0A6459A|SmpB]) [Pubmed|12904796]
  • Expression and Regulation

    Operons

    genes
    [gene|D8851F453E5EF18D36F25834A8CB9C61EAF15E44|secG]-[gene|C0B6520E74CE9F7EE3DEC8C0D83E0770F241C4E8|yvaK]-[gene|0472A4346ADA1DC41C9D00E8F3222A0EBB76DFA8|rnr]-[gene|D19519B5A776D6E8EC2BFE7A7D67469CA0A6459A|smpB]-[gene|5C12BB19B975F7FEBCFA119DAC66338C20FCECFA|ssrA]
    description
    [Pubmed|17369301]

    sigma factors

  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [Pubmed|11544224], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]
  • regulation

  • ''[protein|search|yvaK]'': induced by stress ([protein|search|SigB]) [Pubmed|11544224]
  • view in new tab

    genes
    [gene|D19519B5A776D6E8EC2BFE7A7D67469CA0A6459A|smpB]-[gene|5C12BB19B975F7FEBCFA119DAC66338C20FCECFA|ssrA]
    description
    [Pubmed|17369301]

    regulation

  • ''[protein|search|yvaK]'': [protein|search|SigB] [Pubmed|11544224]
  • view in new tab

    genes
    [gene|C0B6520E74CE9F7EE3DEC8C0D83E0770F241C4E8|yvaK]-[gene|0472A4346ADA1DC41C9D00E8F3222A0EBB76DFA8|rnr]-[gene|D19519B5A776D6E8EC2BFE7A7D67469CA0A6459A|smpB]-[gene|5C12BB19B975F7FEBCFA119DAC66338C20FCECFA|ssrA]
    description
    [Pubmed|17369301]

    regulation

  • ''[protein|search|yvaK]'': induced by stress ([protein|search|SigB]) [Pubmed|11544224]
  • view in new tab

    References

    Reviews

  • 12730326,10881189
  • Original publications

  • 18977770,11395451,17369301,10881189,12904796