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fabL [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]
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fabL [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]

enoyl-acyl carrier protein reductase
locus
BSU08650
pI
5.97
mw
27.00 kDa
function
fatty acid biosynthesis
product
enoyl-acyl carrier protein reductase
essential
no
synonyms
yfhR, ygaA

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.4|Lipid metabolism] → [category|SW 2.4.2|Biosynthesis of lipids] → [category|SW 2.4.2.1|Biosynthesis of fatty acids]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
  • [SW|Categories] containing this gene/protein

  • [SW|biosynthesis of lipids], [SW|sporulation proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|SigG regulon], [SW|SpoVT regulon], [SW|YfhP regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    937,079 -> 937,831

    The protein

    Paralogous protein(s)

  • [protein|search|FabI], one of the two proteins has to be present for viability [Pubmed|17114254]
  • Structure

  • [PDB|3OIC] [Pubmed|21185310]
  • Expression and Regulation

    Operon

  • ''[protein|search|mutY]-[protein|search|fabL]-[protein|search|sspE]'' [Pubmed|10463184]
  • ''[protein|search|fabL]-[protein|search|sspE]'' [Pubmed|10463184]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|10463184], [protein|search|SigG] [Pubmed|15699190]
  • Regulation

  • repressed by [protein|search|YfhP] during exponential growth [Pubmed|10463184]
  • repressed by [SW|SpoVT] during forespore expression [Pubmed|8755877]
  • References

    Reviews

  • 15952903,17919287
  • Original Publications

  • 17114254,10463184,15699190,8755877,11007778,21185310,25527535