gcvH [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

glycine cleavage system protein H, 2-oxo acid dehydrogenase, lipoyl-binding site, octanoyltransferase for lipoic acid biosynthesis

locus: BSU32800

pI: 3.00

mw: 14.00 kDa

function: glycine utilization

product: glycine cleavage system protein H

essential: no

synonyms: yusH

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.2|Utilization of amino acids] → [category|SW 2.3.2.8|Utilization of threonine/ glycine]
• [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.7|Biosynthesis and scavenging of lipoic acid]

[SW|Categories] containing this gene/protein

• [SW|utilization of amino acids], [SW|Biosynthesis of cofactors]

Gene

Coordinates on the chromosome (coding sequence): 3,366,123 -> 3,366,506

The protein

Protein family

• gcvH family (according to Swiss-Prot)

[SW|Cofactors]

• lipoic acid, lipoylated by [protein|search|LipM] [Pubmed|20882995]

Structure

• [PDB|3IFT] (from ''Mycobacterium tuberculosis'', 50% identity) [Pubmed|20364333]

References

Reviews

• 27074917

Original publications

• 20882995,21338421,20364333