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ndh [Tue Dec 13 2016 11:16:32 GMT+0100 (CET)]
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ndh [Tue Dec 13 2016 11:16:32 GMT+0100 (CET)]

NADH dehydrogenase (Menaquinone 7 & no proton)
locus
BSU12290
pI
6.00
mw
41.00 kDa
function
respiration
product
NADH dehydrogenase (Menaquinone 7 & no proton)
essential
no
synonyms
yjlD

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.1|Electron transport and ATP synthesis] → [category|SW 2.1.2|Respiration] → [category|SW 2.1.2.4|Respiration/ other]
  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.9|Newly identified competence genes]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|respiration], [SW|membrane proteins], [SW|most abundant proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|Rex regulon], [SW|stringent response]
  • Gene

    Coordinates on the chromosome (coding sequence)
    1,299,074 -> 1,300,252

    Phenotypes of a mutant

  • inactivation of ''ndh'' facilitates without a wall (due to reduction of oxidative stress) [Pubmed|26051891]
  • The protein

    Protein family

  • NADH dehydrogenase family (according to Swiss-Prot)
  • Structure

  • [PDB|4NWZ] (from ''C. thermarum'', 42% identity) [Pubmed|24444429]
  • [SW|Localization]

  • membrane associated [Pubmed|18763711]
  • [SW|Interactions]

  • [protein|search|Mdh]-[protein|search|Ndh] [Pubmed|20933603]
  • Expression and Regulation

    Operon

  • ''[protein|search|yjlC]-[protein|search|ndh]'' [Pubmed|17015645]
  • Regulation

  • [protein|search|RelA] dependent downregulation (Class I) during stringent response [Pubmed|11948165]
  • induced under anaerobic conditions ([protein|search|Rex]) [Pubmed|17015645]
  • Regulatory mechanism

  • [protein|search|Rex]: transcription repression [Pubmed|17015645]
  • Additional information

  • belongs to the 100 [SW|most abundant proteins] [PubMed|15378759]
  • References

  • 17015645,20933603,11948165,18763711,15378759,26051891,24444429