rsbQ

alpha/beta hydrolase, required for [protein|9284E58A2D5394A31658E70879874A1338CF531B|RsbP] activation

locus: BSU_34100

pI: 5.00

mw: 29.87 kDa

protein length: 269 aa

gene length: 810 bp

function: control of [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB] activity

product: alpha/beta hydrolase

essential: no

synonyms: yvfQ

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.2|Control of sigma factors]

Gene

Coordinates: 3,499,541 3,500,350

The protein

Protein family

• [SW|AB hydrolase superfamily] (according to UniProt)

[SW|Domains]

• [SW|AB hydrolase-1 domain] (aa 23-259) (according to InterPro)

Structure

• [PDB|1WOM] [Pubmed|15632289]

Expression and Regulation

Operons

• genes: [gene|9284E58A2D5394A31658E70879874A1338CF531B|rsbP]-[gene|53496D7AC05B20C5AEB6CB9B9B8825FC987B12C5|rsbQ]
  description: [Pubmed|22383849]

Biological materials

Mutant

• MGNA-A480 (yvfQ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/480 NBRP B. subtilis, Japan]
• BKE34100 ([gene|53496D7AC05B20C5AEB6CB9B9B8825FC987B12C5|rsbQ]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE34100 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGATTGGCTCCTTTCAGC, downstream forward: _UP4_TGATATAGGAACGAAAGGGA
• BKK34100 ([gene|53496D7AC05B20C5AEB6CB9B9B8825FC987B12C5|rsbQ]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK34100 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGATTGGCTCCTTTCAGC, downstream forward: _UP4_TGATATAGGAACGAAAGGGA

labs

• [SW|Chet Price], Davis, USA [http://foodscience.ucdavis.edu/price_lab/pricelab.html homepage]

References

Reviews

• 33042030

Original publications

• 15632289,11591687,19432806,27977677,32075967