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gltT [Fri Dec 09 2016 17:22:59 GMT+0100 (CET)]
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gltT [Fri Dec 09 2016 17:22:59 GMT+0100 (CET)]

major high-affinity Na -coupled glutamate/ aspartate symport protein
locus
BSU10220
pI
9.00
mw
45.00 kDa
function
glutamate and aspartate uptake
product
major Na -coupled glutamate/ aspartate symport protein
essential
no
synonyms
yhfG

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.1|Amino acid transporters] → [category|SW 1.2.4.1.1|Solute:sodium symporter family]
  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.1|Amino acid transporters] → [category|SW 1.2.4.1.6|Dicarboxylate/amino acid:cation symporter]
  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.1|Biosynthesis/ acquisition of glutamate/ glutamine/ ammonium assimilation]
  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.2|Utilization of amino acids] → [category|SW 2.3.2.1|Utilization of glutamine/ glutamate]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|transporters/ other], [SW|biosynthesis/ acquisition of amino acids], [SW|glutamate metabolism], [SW|utilization of amino acids], [SW|membrane proteins]
  • Gene

    Coordinates on the chromosome (coding sequence)
    1,096,560 -> 1,097,849

    Phenotypes of a mutant

  • impaired uptake of glutamate and aspartate [Pubmed|25344233]
  • The protein

    Protein family

  • View classification (according to Swiss-Prot)
  • Paralogous protein(s)

  • [protein|search|GltP], [protein|search|DctP]
  • Structure

  • [PDB|4IZM] (the protein from ''Pyrococcus horikoshii'', 35% identity, 73% similarity) [Pubmed|23563139]
  • [http://pdb.org/pdb/explore/explore.do?structureId=4KY0 4KY0] (the glutamate transporter of ''Thermococcus kodakarensis'', 35% identity, 72% similarity) [Pubmed|24013209]
  • [SW|Localization]

  • cell membrane [Pubmed|18763711]
  • Expression and Regulation

    Operon

  • ''gltT'' [Pubmed|22383849]
  • Biological materials

    Mutant

  • available in [SW|Erhard Bremer]'s lab [Pubmed|25344233]
  • References

  • 18763711,23563139,22383849,24013209,25344233