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ispA [Mon Aug 31 2015 13:53:53 GMT+0200 (CEST)]

intracellular serine protease

locus: BSU13190

pI: 4.52

mw: 33.00 kDa

function: protein degradation

product: intracellular serine protease

essential: no

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.3|Utilization of nitrogen sources other than amino acids] → [category|SW 2.3.3.5|Utilization of proteins]
• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.7|Proteolysis] → [category|SW 3.3.7.4|Additional proteins involved in proteolysis]

[SW|Categories] containing this gene/protein

• [SW|utilization of nitrogen sources other than amino acids], [SW|proteolysis], [SW|sporulation proteins]

This gene is a member of the following [SW|regulons]

• [SW|CodY regulon]

The protein

Protein family

• peptidase S8 family (according to Swiss-Prot)

[SW|Localization]

• cytoplasm (according to Swiss-Prot)

Expression and Regulation

Operon

• ''ispA'' (according to [http://dbtbs.hgc.jp/COG/prom/ispA.html DBTBS])

[SW|Sigma factor]

• [protein|search|SigA] [Pubmed|3087947]

Regulation

• repressed during growth in the presence of branched chain amino acids ([protein|search|CodY]) [Pubmed|23569278]

Regulatory mechanism

• [protein|search|CodY]: transcription repression [Pubmed|23569278]

References

• 3087947,23569278