SubtiBank SubtiBank
ytnP [2017-8-11 16:0:3]
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ytnP [2017-8-11 16:0:3]

lactonase-homolog protein, inhibits the signalling pathway required for the streptomycin production and development of aerial mycelium in Streptomyces griseus
locus
BSU29890
pI
5.93
mw
29.02 kDa
protein length
256 aa Sequence Blast
gene length
768 bp Sequence Blast
function
defense against competing bacteria
product
lactonase-homolog protein
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.13|Resistance against toxins/ antibiotics]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.5|Phosphorylation on a Ser residue]

    • Gene

    Coordinates
    3,058,631 → 3,059,401

    The protein

    Modification

  • phosphorylation on Ser-36 [Pubmed|17218307]

    • Structure

  • [PDB|3ESH] (from Staphylococcus aureus, 50% identity)

    • Expression and Regulation

    Operons

    genes
    [gene|53259B300509E6B6DAF3ED106D1DDEDC99B5532B|ytnP]-[gene|BBBCD5F56779895189E21076AF165B901F654534|malS]
    description
    [Pubmed|22383849]
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    Biological materials

    Mutant

  • MGNA-A511 (ytnP::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/511 NBRP B. subtilis, Japan]

    • References

  • 17218307,22101040