SubtiBank SubtiBank
sacX [Mon Aug 31 2015 13:57:29 GMT+0200 (CEST)]
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

sacX [Mon Aug 31 2015 13:57:29 GMT+0200 (CEST)]

trigger enzyme: sucrose-specific phosphotransferase system, EIIBC component of the PTS (low affinity) and control of SacY activity
locus
BSU38410
pI
9.35
mw
48.00 kDa
function
sucrose uptake and phosphorylation, control of SacY activity
product
trigger enzyme: sucrose-specific phosphotransferase system,
EIIBC component (low affinity)
essential
no
ec
2.7.1.69
synonyms
ipa-14r, sacS

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.2|Phosphotransferase system] → [category|SW 1.2.2.2|Sugar specific PTS proteins]
  • [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.19|Utilization of sucrose]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.4|Control of PRD-type regulators]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.3|Trigger enzyme] → [category|SW 3.4.3.1|Trigger enzymes of the PTS that control the activity of PRD-containing transcription factors]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.3|Phosphorylation on a Cys residue]
  • syns
    ipa-14r, sacS

    [SW|Categories] containing this gene/protein

  • [SW|phosphotransferase systems], [SW|utilization of specific carbon sources], [SW|transcription factors and their control], [SW|trigger enzyme], [SW|membrane proteins], [SW|phosphoproteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|SacY regulon]
  • The protein

    Catalyzed reaction/ biological activity

  • Protein EIIB N(pi)-phospho-L-histidine/cysteine + sugar = protein EIIB + sugar phosphate (according to Swiss-Prot)
  • Protein family

  • [SW|PTS] permease, sucrose permease (Scr) family [Pubmed|10627040]
  • [SW|Localization]

  • cell membrane (according to Swiss-Prot)
  • Expression and Regulation

    Operon

  • ''[protein|search|sacX]-[protein|search|sacY]'' [Pubmed|2116367]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|1400159]
  • Regulation

  • induction by sucrose (at high concentration) [Pubmed|8535520]
  • Regulatory mechanism

  • induction by [protein|search|SacY]-dependent [SW|RNA switch] (transcriptional antitermination) [Pubmed|8535520]
  • [protein|search|DegU]-P: transcription activation [Pubmed|1400159]
  • References

  • 10627040,2105292,2116367,1400159,8535520