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cpgA
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cpgA

ribosome assembly GTPase, activity stimulated by ribosomes, may be involved in the maturation of the 30S subunit of the ribosome, detoxification of 4-phosphoerythronate
Locus
BSU_15780
Isoelectric point
4.74
Molecular weight
33.64 kDa
Protein length
298 aa Sequence Blast
Gene length
897 bp Sequence Blast
Function
ribosome assembly, coordination of peptidoglycan deposition in the cell wall, metabolite proofreading
Product
GTPase
Essential
no
Synonyms
yloQ,rsgA

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
1,653,103 1,653,999

Phenotypes of a mutant

  • forms curly cells PubMed
  • poor growth PubMed
  • non-transformable PubMed
  • defective in 16S rRNA 3' processing by YqfG PubMed
  • The protein

    Catalyzed reaction/ biological activity

  • dephosphorylation of 4-phosphoerythronate thus preventing inhibition of GndA PubMed
  • Protein family

  • TRAFAC class YlqF/YawG GTPase family (together with RbgA and YqeH, according to UniProt)
  • Domains

  • CP-type G domain (aa 67-228) (according to UniProt)
  • Modification

  • in vitro phosphorylated on Thr-166 by PrkC, dephosphorylated by PrpC PubMed
  • Structure

    Expression and Regulation

    Biological materials

    Mutant

  • MGNA-B135 (yloQ::erm), available at the NBRP B. subtilis, Japan
  • BKE15780 (cpgA::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CTCAGGCATATTTTCCCTCC, downstream forward: _UP4_GACAGAAAGCCGAGGTATTA
  • BKK15780 (cpgA::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CTCAGGCATATTTTCCCTCC, downstream forward: _UP4_GACAGAAAGCCGAGGTATTA
  • Labs working on this gene/protein

  • Tony Wilkinson, York University, U.K. homepage
  • References

    Reviews

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    Original publications

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