You are currently viewing an outdated version of
SubtiWiki.
Please use
the newest version!
feuA [2017-03-14 14:10:17]
ABC transporter for the siderophores Fe-enterobactin and Fe-bacillibactin (binding protein), with YusV as ATPase
function
acquisition of iron
product
ABC transporter for the siderophores Fe-enterobactin
and Fe-bacillibactin (binding protein) [pubmed|28283524]
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.5|Uptake of iron/ siderophores][category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.3|Acquisition of iron] → [category|SW 1.3.3.1|ABC transporters for the uptake of iron/ siderophores][category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.5|Iron metabolism] → [category|SW 2.6.5.4|ABC transporters for the uptake of iron/ siderophores][category|SW 6|Groups of genes] → [category|SW 6.12|Secreted proteins][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]This gene is a member of the following [SW|regulons]
[SW|Btr regulon], [SW|Fur regulon], [SW|CitB regulon] (putative)Gene
Coordinates on the chromosome (coding sequence)
182,370 -> 183,323
The protein
Protein family
Fe/B12 periplasmic-binding domain (according to Swiss-Prot)[SW|Domains]
Two independent non-symmetric globular domains, connected by a long alpha-helix (residues 143-164 of the mature protein).Modification
FeuA is a lipoprotein with a N-acetyl-S-diacyl-glyceryl-cysteine structure [Pubmed|22303020]Structure
[PDB|2PHZ], [PDB|2WI8], [PDB|2WHY] (complex with ferri-bacillibactin), [PDB|2XUZ] (complex with ferri-enterobactin), [PDB|2XV1] (complex with ferric mecam)[SW|Localization]
associated to the membrane (lipoprotein) [Pubmed|22303020]extracellular (signal peptide) [Pubmed|18957862]Expression and Regulation
[[this]]
References
20086155,19746494,19673474,14563870,16672620,10092453,16889643,17725565,12354229,18957862,18763711,22303020,10468622,28283524 
